Allgemein

June 2019. Our study characterizes the structure and dynamics of phospholipid bilayers close to phase transition employing atomistic molecular dynamics simulations. The simulations recover not only the well-studied first-order transition with discontinuities in the area per lipid or membrane thickne...

December 2017. Liping Sun of the Computational Biology group successfully defended her thesis with the title „Biomembrane Dynamics: From Membrane Thermodynamics to Protein Design“. Congratulations!

November 2016. SNARE peptides act cooperatively during synaptic vesicle fusion. It has previously been suggested that oligomerization of SNARE complexes, which is required for cooperative action in fusion is mediated by interactions between their transmembrane domains (TMDs) and further tuned by int...

November 2016. Combination of NMR and CD experiments with MD simulations revealed the dual role of the model fusion peptide K in aiding membrane fusion. Next to the before known function of peptide K to form a coiled-coil complex with peptide E and thus to link the fusion vesicles, the membrane-dist...

November 2016. Simulations reveal new insights into the function of a protein involved in cancer metastasis and AIDS Cholesterol may act as a selective glue that binds proteins into paired structures that enable human cells to respond to outside signals, according to our new study in PLOS Computa...

August 2016. Zhenyan Jiang of the Computational Biology group successfully defended his thesis with the title "BAX Activation and Oligomerization in Membranes Studied by Coarse-Grained and All-Atom Simulations". Congratulations!

July 2016. Kristyna Pluhackova won the first Young Investigator grant announced by the Biology Department of FAU. Congratulations!

July 2016. Hansi Zhang of the Computational Biology group successfully defended her thesis with the title "Molecular Insight into the Sphingosine-1-Phosphate Pathway: From the Unbinding from ApoM to Receptor Activation". Congratulations!

June 2016. Sonja Kirsch of the Computational Biology Group was awarded the Luise-Prell-Award 2016 for her outstanding master thesis in Integrated Life Sciences - congratulations!