September 2019. Dendritic cells (DCs) are key players in the immune system as they orchestrate the initiation of immune responses, but also the induction of tolerance. DC signaling response and the host recognition of invading pathogens primarily rely on receptors that are highly expressed on the ce... Weiterlesen

June 2019. Our study characterizes the structure and dynamics of phospholipid bilayers close to phase transition employing atomistic molecular dynamics simulations. The simulations recover not only the well-studied first-order transition with discontinuities in the area per lipid or membrane thickne... Weiterlesen

December 2017. Liping Sun of the Computational Biology group successfully defended her thesis with the title „Biomembrane Dynamics: From Membrane Thermodynamics to Protein Design“. Congratulations! Weiterlesen

November 2016. SNARE peptides act cooperatively during synaptic vesicle fusion. It has previously been suggested that oligomerization of SNARE complexes, which is required for cooperative action in fusion is mediated by interactions between their transmembrane domains (TMDs) and further tuned by int... Weiterlesen

November 2016. Simulations reveal new insights into the function of a protein involved in cancer metastasis and AIDS Cholesterol may act as a selective glue that binds proteins into paired structures that enable human cells to respond to outside signals, according to our new study in PLOS Computa... Weiterlesen

August 2016. Zhenyan Jiang of the Computational Biology group successfully defended his thesis with the title "BAX Activation and Oligomerization in Membranes Studied by Coarse-Grained and All-Atom Simulations". Congratulations! Weiterlesen

July 2016. Kristyna Pluhackova won the first Young Investigator grant announced by the Biology Department of FAU. Congratulations! Weiterlesen

July 2016. Hansi Zhang of the Computational Biology group successfully defended her thesis with the title "Molecular Insight into the Sphingosine-1-Phosphate Pathway: From the Unbinding from ApoM to Receptor Activation". Congratulations! Weiterlesen

June 2016. Sonja Kirsch of the Computational Biology Group was awarded the Luise-Prell-Award 2016 for her outstanding master thesis in Integrated Life Sciences - congratulations! Weiterlesen